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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf48
All Species:
6.36
Human Site:
Y460
Identified Species:
14
UniProt:
Q9NWS1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS1
NP_060385.2
579
65081
Y460
S
K
P
L
C
V
L
Y
M
E
N
D
L
S
E
Chimpanzee
Pan troglodytes
XP_509318
760
85084
Y641
S
K
P
L
C
V
L
Y
M
E
N
D
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001085518
579
65125
H460
P
K
P
L
C
V
L
H
M
E
N
D
L
S
E
Dog
Lupus familis
XP_855025
579
65071
H460
S
K
P
L
S
I
L
H
V
E
N
D
F
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRT3
573
64087
L458
K
P
L
S
A
L
H
L
E
D
D
V
S
E
G
Rat
Rattus norvegicus
Q9EQ10
573
63884
R458
S
K
P
L
S
A
L
R
L
E
N
D
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507285
579
64417
T460
P
S
A
R
C
F
L
T
L
Q
S
G
W
F
K
Chicken
Gallus gallus
Q5ZKL9
580
65236
A458
V
P
A
C
M
H
P
A
P
K
Q
H
L
H
G
Frog
Xenopus laevis
Q32N66
567
63030
P455
Q
V
P
S
C
I
H
P
A
P
K
I
V
P
V
Zebra Danio
Brachydanio rerio
Q1RMA6
568
62451
P449
Q
I
P
T
C
V
H
P
A
P
K
K
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178396
861
96268
L650
K
K
K
K
G
A
P
L
V
K
G
Q
Q
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
94.4
82.3
N.A.
69.2
68.7
N.A.
63.2
54.4
50
39.3
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
75.5
96.7
90.6
N.A.
81.3
80.6
N.A.
78.4
72
64.5
56.6
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
86.6
66.6
N.A.
0
66.6
N.A.
13.3
6.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
20
80
N.A.
40
13.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
19
0
10
19
0
0
0
10
0
0
% A
% Cys:
0
0
0
10
55
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
46
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
46
0
0
0
10
46
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
10
0
0
19
% G
% His:
0
0
0
0
0
10
28
19
0
0
0
10
0
10
0
% H
% Ile:
0
10
0
0
0
19
0
0
0
0
0
10
0
0
0
% I
% Lys:
19
55
10
10
0
0
0
0
0
19
19
10
0
0
10
% K
% Leu:
0
0
10
46
0
10
55
19
19
0
0
0
37
0
10
% L
% Met:
0
0
0
0
10
0
0
0
28
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% N
% Pro:
19
19
64
0
0
0
19
19
10
19
0
0
0
10
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
10
10
10
10
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
37
10
0
19
19
0
0
0
0
0
10
0
10
55
10
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% T
% Val:
10
10
0
0
0
37
0
0
19
0
0
10
19
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _